Stem Cell Treatment For COPD

Stem Cell Treatment For COPD

Chronic Obstructive Pulmonary Disease is a degenerative condition of the lungs. Overtime, long term injury to the parnechyma results in restricted airways and hyperinflation of the lungs. The thickening of airways increases airway resistance resulting in air trapping .These progressive changes decrease quality of life, leading to disability and eath. Emphysema is profoundly caused by smoking and unfortunately, long after the smoke exposure ceases, the inflammatory process persists.

Symptoms and Treatment of COPD

The symptoms of COPD include shortness of breath, reduced exercise tolerance, fatigue and chronic wet cough. These symptoms are managed by the use of steroids to suppress the immune system. Antibiotics are given for recurring infections such as pneumonia. The downside of these treatments is that the patient is at increased risk for infections and cancer due to long term suppression of the immune system. These medications simply control the symptoms but further weaken the patient as a whole. Unfortunately, with this medical model COPD is terminal and will cause disability and death.

Mesenchymal stem cells (MSC’s) are showing promising results for even advanced patients. The mesenchymal stem cells modulate the immune system by inhibiting the overactive chemicals such as IL-6 and enhancing the regulatory T cells. The MSC’s stimulate the body’s own regenerative and repair capabilities in the areas of injured tissue. The stem cells via paracrine signaling travel to the lungs and begin secreting growth factors and cytokines to begin repair.

Umbilical cord derived stem cells (UCB-MSC’s) have the advantage of bone marrow derived stem cells (BM-MSC’s) due to their smaller size. This prevents possible pulmonary entrapment that has occured with some infusions of BM-MSC’s. Most COPD patients are older and generally unhealthy. The bone marrow derived stem cells from the patient reflect the poor health of the host. UCB-MSC’s are just 9 months old and have been shown to be more robust than the BM-MSC’s and respond strongly to paracrine signaling compared to the BM-MSC’s.

The treatment for COPD is simple and results are seen quickly.  For more information on how this treatment can help you call 480-535-7868 or click here to request a complimentary consult with the physician.

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